Our Core Material
Dazzeon’s MannanPRO® is a medicinal-grade, high-purity extract derived from the inner gel of aloe vera—free from the toxic aloin.
Our proprietary process efficiently isolates Acemannan, an acetylated mannan polysaccharide with proven clinical benefits, including mucosal repair, antibacterial and anti-inflammatory effects, wound healing, gastrointestinal ulcer mitigation, liver protection, and constipation improvement. Recent studies further indicate its potential to inhibit tumor growth and boost immune responses, supporting its use in cancer prevention and treatment.
Over the past two years, we have refined our in-house purification technology using fully equipped production, quality assessment, and microbial testing laboratories. The final extract is rigorously characterized via nuclear magnetic resonance calibrated against a US Pharmacopeia standard.
Dazzeon’s Technology reaches
Peerless in the world
| Company | Extraction Process | Acemannan Purity | Quality Notes |
|---|---|---|---|
| DAZZEON® (Taiwan) | Proprietary extraction technology — delivers ultra-high purity | Achieves ≥ 110 kDa, ＞ 90 % polysaccharides (Acemannan) | The only large-scale GMP-compliant extraction process in the world; produces pharmaceutical-grade “MannanRx™”, aloin-free, stability ＞ 2 years |
| Brand N (Costa Rica) | Ethanol precipitation & freeze-drying — uncontrolled, broad MW distribution | Top-grade yield 65 %; also offers a 20–25 % grade | Full-spectrum (deleterious matrix effects); uses hand-filleted gel only; shelf-life ＞ 5 years |
| Brand A (USA) | Aseptic processing & low-temperature drying — patented; stabilises ≥ 10 % polysaccharides | ~ 10 % (full spectrum) | Commodity-grade aloe; emphasises batch-scale consistency; polysaccharide range centred on 50–200 kDa |
| Generic Chinese suppliers / researchers | Highly variable: solvent extraction, enzyme-assisted methods, or simple dehydration | ＜ 5 % to ~ 95 %, depending on product | Lower-end products may be mislabelled or degraded (some test only for “aloe polysaccharide”); a few offer ＞ 90 % research-grade. Widely varying standards demand rigorous QC. |
Commercial
MannanPRO®
2 years of stability and counting
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(Lee et al., 2018, DOI: 10.3390/jfb9030046)
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Cosmetic Safety and Efficacy Tests
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HC116 Cells
