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Patented Processes

Patented Processes

Process Introduction

Throughout human civilization, various herbs have been widely utilized for their medicinal properties. However, due to the complex composition of these herbs, processing and refining are necessary to extract effective components and enhance their therapeutic effects. This necessity marks the origin of purification technology. As the concentration of target substances is increased, the concentration of potentially harmful substances may also rise, posing a significant challenge in precisely retaining active substances.

DAZZEON Biotech has recognized the substantial potential and broad applicability of plant polysaccharides. The company has collaborated with a prominent pharmaceutical technology center to develop an “Plant Polysaccharide -Acemannan HPLC Analysis Platform.” Subsequently, DAZZEON Biotech has strengthened its research and development resources and talent, fostering technological innovation and patent accumulation, while also optimizing production processes. These efforts have accelerated DAZZEON Biotech’s advancements in biomedical research and production, laying a solid foundation for its future development.

Technological Innovations and Patents

Acemannan are present in water-soluble aloe extracts, and various extraction methods have been documented to date. However, these methods are typically of laboratory scale and face challenges such as low yields from single-use processes, or they have been adapted for industrial-scale production but result in overly crude processes with low polysaccharide concentrations.

Additionally, commercially available crude aloe extract powders often suffer from issues such as moisture sensitivity, clumping, poor stability, yellowing, and poor water solubility, necessitating further refining processes to enhance the final product quality, which in turn increases costs.

DAZZEON Biotech’s MannanPRO® powder features a low degradation rate and high quality, advantages that have led to the acquisition of patents in the United States (US11654177B2), Taiwan (TWI752622B), and China (CN114149512B).

Process Optimization Capabilities

DAZZEON Biotech’s process optimization capabilities are showcased through its continuous innovation and commitment to improving product quality.

Firstly, through meticulous process control and advanced testing techniques, the company has successfully increased the concentration of acemannan to 95%. This achievement not only highlights its leadership in extraction technology but also sets new standards for product specifications and market competitiveness.

Secondly, by conducting in-depth studies on the impact of different processes on bioactivity, DAZZEON Biotech maximizes the developmental applicability of products, ensuring that all innovations meet both high efficiency and high-quality standards.

Additionally, DAZZEON Biotech operates its own manufacturing facilities, which adhere strictly to ISO and HACCP standards. This adherence ensures the safety and hygiene of the processes and also demonstrates DAZZEON Biotech’s responsibility and professionalism in manufacturing practices.

These exceptional process optimization capabilities not only solidify DAZZEON Biotech’s status as an industry leader but also ambitiously propel the company toward developing a diverse range of high-grade materials and achieving global standardization.

Research Outcomes

Advanced instrumentation, including High-Performance Liquid Chromatography (HPLC), Fourier-Transform Infrared Spectroscopy (FT-IR), and Nuclear Magnetic Resonance (NMR) analysis, has confirmed that our products contain high-purity polysaccharides and critical active functional groups.

Furthermore, tests have confirmed the absence of aloin (barbaloin) in our products, ensuring compliance with the regulatory standards set by the International Aloe Science Council (IASC) in the United States and the Ministry of Health and Welfare in Taiwan. This adherence to stringent quality standards highlights our commitment to delivering safe and highly effective products.